U.S. EPA to eliminate all mammal testing by 2035

first_img U.S. EPA to eliminate all mammal testing by 2035 The U.S. Environmental Protection Agency (EPA) in Washington, D.C., announced today that it will stop conducting or funding studies on mammals by 2035. The move, which is already eliciting strong reactions from groups supporting or opposing experiments on animals, makes EPA the first federal agency to put a hard deadline on phasing out animal research.EPA’s decision “is a decisive win for taxpayers, animals, and the environment,” says Justin Goodman, vice president of advocacy and public policy at the White Coat Waste Project, a Washington, D.C.–based animal activist group that has slammed such research as a waste of taxpayer money. “Animal tests are unreliable and misleading,” he asserts.But Jennifer Sass, a senior scientist at the Natural Resources Defense Council, a Washington, D.C.–based environmental group, blasts EPA’s decision. “It’s very disappointing and very frustrating,” Sass says. Ending animal testing, she argues, “is going to allow potentially dangerous chemicals to get out there into the environment and into consumer products.”Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*) EPA relies on animal testing to gauge the safety of chemicals, whether it be a new pesticide or a potential pollutant in the environment. But chemical companies have long complained that the tests—many of which they pay for—are expensive and time-consuming. And animal advocacy organizations have urged the agency to move toward nonanimal models, such as computer programs and “organ-on-a chip” technology, a collection of cells designed to mimic entire organs. Legislation, including a 2016 amendment to the Toxic Substances Control Act, has required EPA to move away from animal experiments.In June, EPA Administrator Andrew Wheeler sent an internal memo outlining a plan to eventually phase out the agency’s animal testing, first reported by The Intercept. In the memo, which became official today, Wheeler writes that “animal testing is expensive and time-consuming,” and that scientific advances that don’t involve animals are allowing researchers to evaluate chemicals faster, more accurately, and at lower cost. The agency, he writes, will redirect its resources toward these “New Approach Methods” and away from animal testing. “The EPA will reduce its requests for, and our funding of, mammal studies by 30 percent by 2025 and eliminate all mammal study requests and funding by 2035.” After that date, any studies will require administrator approval.At a news conference in Washington, D.C., this morning, Wheeler also announced $4.25 million in funding to five institutions to develop nonanimal alternatives to current tests: Johns Hopkins University in Baltimore, Maryland; Vanderbilt University and Vanderbilt University Medical Center, both in Nashville; Oregon State University in Corvallis; and the University of California, Riverside.It’s not clear how many animals or research projects will be affected by the changes. EPA says the total number of animals used in toxicology studies submitted to the agency annually ranges from 20,000 to more than 100,000. Goodman estimates there are about 20,000 animals in EPA labs—including rabbits, mice, and rats—most of which are used to gauge the safety of environmental pollutants such as smog and ozone. Other animals—including rabbits, guinea pigs, and dogs—are tested by chemical companies (or the testing is outsourced to contract research organizations) to meet EPA requirements on the safety of new products. Goodman says the new EPA policy will affect both realms. Companies will no longer to need to use as many—or any animals—to meet EPA standards, and the agency itself will no longer conduct mammal testing. (Goodman says some toxicology testing is conducted on fish, and he expects that to continue.)“This is the most comprehensive and aggressive plan in U.S. history to cut government animal testing,” Goodman says. “I think it’s going to be the gold standard for other agencies.”Sass says she’s concerned that EPA’s proposed changes will give the chemical industry, which will need to develop its own nonanimal alternatives, too much control over these technologies. “A lot of nonanimal tests are done by contractors, so they’re proprietary,” she says. “There’s no way for experts to evaluate how these chemicals are tested. You’re going to have a black box funded by industry.”At the press conference, Wheeler denied that the policy shift was influenced by chemical companies. Instead, he said he was motivated by his mother, who is an animal lover, and his zoologist and veterinarian sisters. EPA has also recently teamed up with the animal rights group People for the Ethical Treatment of Animals (PETA), and representatives from PETA, the White Coat Waste Project, and the Humane Society of the United States took part in today’s press conference.Sass says even though scientists have made great strides in creating nonanimal models, they’re often still no match for the real thing. She notes that to determine whether a chemical causes a disease like lupus, researchers need to see the impact on the entire immune system, not just a few cells in a dish or on a computer. And the learning disabilities caused by lead poisoning would not have been picked up without animal experiments, she says. “You can’t test whether a cell has ADHD [attention deficit hyperactivity disorder].”Ann Bartuska, vice president for land, water, and nature at Resources for the Future, a Washington, D.C.–based nonprofit that conducts independent research into environmental and energy issues, says Sass raises legitimate concerns. “The process needs to be transparent so others can evaluate how effective these new approaches are.”But Bartuska, a former deputy undersecretary at the U.S. Department of Agriculture (which conducts and funds numerous animal studies), notes that EPA has a science advisory board that will oversee the plan, and she says the agency has given itself enough time to make sure nonanimal alternatives work before it completely phases out its mammal research. “It’s a very major step that I think will have an impact on other federal agencies,” she says. “It’s right to be cautious, but something has to change.” iStock.com/ unoL By David GrimmSep. 10, 2019 , 6:00 PMlast_img

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